Cultural Adaptations of Evidence-Based Interventions for Latinx Populations is a publication produced by the National Hispanic and Latino Mental Health Technology Transfer Center (National Hispanic and Latino MHTTC). The main goals of the publication are to help educators and supervisors train clinicians to culturally adapt existing evidence-based treatments (EBTs) for the Latinx population they serve; describe an array of cultural adaptation models, frameworks, and methods; highlight the benefits and challenges of undertaking cultural adaptations, and provide recommendations and resources to culturally adapt and implement an existing EBT.