Unaccompanied minors from Guatemala, Honduras, and El Salvador make up 48%, 27%, and 14%, respectively, of all unaccompanied minors arriving to the United States. Raising awareness of the traumatic experiences, background, developmental history, and mental health needs of unaccompanied minors and understanding this information in the context of the child's culture and national origin is critical to better serve their mental health needs. This factsheet provides tips for clinicians working with Hispanic unaccompanied children who have been detained and reunited with family members.