Latinxs living in the US experience disparities in access and quality of mental health services. The social determinants of health, immigration status, immigration-related trauma, and the cumulative experience of inequality, combined with the vulnerability during pregnancy and postpartum may result in a higher risk for mental health symptoms. Perinatal Mental Health Disorders (PMHDs) is a term used to include the various disorders that can affect individuals during pregnancy and postpartum. This factsheet provides relevant information on cultural considerations for mental health providers working with Latinx populations experiencing or at risk for PMHDs.