This presentation occurred on April 7, 2022 and was facilitated by Dr. Roberto Lewis-Fernandez and Dr. Neil Krishan Aggarwal. This webinar describes the role of culture in the experience of and presentation of mental health problems by individuals seeking care and in assessments and treatments offered by providers. The value of a person-centered cultural assessment was presented, focusing on cultural concepts of distress, social determinants of mental health, and treatment planning and engagement. The Cultural Formulation Interview was introduced as a standardized method for person-centered assessment that appears in DSM-5.